Genomics

See Also

• Dopamine Beta Hydroxylase and ABO Groups
• Reduced platelet MAO activity in healthy male students with blood group O

Description

• Gene type: protein coding
• Gene name: NEUROD2
• Gene description: neurogenic differentiation 2
• Chromosome: 17; Location: 17q12
• Organism: Homo sapiens
• Gene aliases: NDRF; MGC26304

Summary

This gene encodes a member of the neuroD family of neurogenic basic helix-loop-helix (bHLH) proteins. Expression of this gene can induce transcription from neuron-specific promoters, such as the GAP-43 promoter, which contain a specific DNA sequence known as an E-box. The product of the human gene can induce neurogenic differentiation in non-neuronal cells in Xenopus embryos, and is thought to play a role in the determination and maintenance of neuronal cell fates.

Discussion

NeuroD2 is necessary for development and survival of central nervous system neurons. [1]

A possible impact of the neuroD2 transcription factor on the development of drug abusing behavior. [2]

Links