BT005B

TypeZyme B


TAGS:    DIGESTION

ABO specific digestive enzyme complex

INTRODUCTION

The chemical process of digestion depends upon enzymes to break down complex food components (e.g., polysaccharides, fats, and proteins) into their absorbable forms (e.g., monosaccharides, fatty acids, and amino acids) for bodily use. These enzymes are secreted by cells or glands in the gastric mucosa as well as directly from exocrine glands including the salivary gland, pancreas, gallbladder, and liver. [1] Impediments to chemical digestion can lead to maldigestion, malabsorption, changes to the pH of the GI tract, and hence alterations to the microbiome.

Supplementing with digestive enzymes has been shown to improve digestion and restore balance when chemical digestion has been disrupted. This can lead to improvements in gastroesophageal reflux, dysbiosis, dyspepsia, and even inflammatory GI disorders. [2]

Typezyme formulas have been designed by Dr. Peter J. D’Adamo with blood type specificity in mind. His identification of blood-type-associated digestive patterns guided formulations that optimize nutrient breakdown and assimilation while reducing symptoms of maldigestion for each type.

Variations between the blood types regarding the production and array of digestive enzymes have been extensively reported in the medical literature. In fact, the level of certain digestive enzymes can vary by as much as a four-fold difference when one considers just   ABO blood type and secretor status. That’s why I thought it was important to develop a line of enzymes that took the strengths and weaknesses of each blood type into account. Now after over two years of development and testing, we’re ready to release these new TypeZyme formulas.

As with all DPN. Products, these formulas as assayed for potency, and screened for heavy metals and unwanted microbial activity. The individual ingredients have been sourced from around the world and selected by our technical team for maximum bioactivity. I believe these are the best digestive support formulas available.

 


DESCRIPTION/ BACKGROUND

 The chemical process of digestion depends upon enzymes to break down complex food components (e.g., polysaccharides, fats, and proteins) into their absorbable forms (e.g.,monosaccharides, fatty acids, and amino acids) for bodily use. These enzymes are secreted by cells or glands in the gastric mucosa as well as directly from exocrine glands including the salivary gland, pancreas, gallbladder, and liver. [1] Impediments to chemical digestion can lead to maldigestion, malabsorption, changes to the pH of the GI tract, and hence alterations to the microbiome.

Supplementing with digestive enzymes has been shown to improve digestion and restore balance when chemical digestion has been disrupted. This can lead to improvements in gastroesophageal reflux, dysbiosis, dyspepsia, and even inflammatory GI disorders. [2]

TypeZyme formulas have been designed by Dr. Peter J. D’Adamo with blood type specificity in mind. His identification of blood-type-associated digestive patterns guided formulations that optimize nutrient breakdown and assimilation while reducing symptoms of maldigestion for each type.

  • Ovine Pancreas- This blend of pancreatic enzymes from sheep sources, specifically beneficial for blood type B, aids in the breakdown of proteins and lipids.
  • Alpha Amylase- This enzyme is often the first step in digestion as it is secreted by salivary glands and again in the pancreas. Amylase aids with metabolism of sugars and improves intestinal permeability. [3]
  • Lipase- Lipase is typically secreted by the pancreas to break down lipids. Supplementation with lipase has been shown to correct pancreatic insufficiencies and reduce bloating and discomfort following high-fat meals. [4,5]
  • Ox Bile- Ox bile has an ancient history of use in Traditional Chinese Medicine in the treatment of jaundice and intestinal parasites. It was also used to reduce hemorrhoids due to astringent properties. Modern use of ox bile has shown efficacy in the treatment of steatorrhea as it is a fat emulsifier.[6]


AGENT/ INGREDIENT ROLE
Ox Bile

TABLE 1: Key agents in TypeZyme B.

ACTIONS/ INDICATIONS

Naturopathic approaches to digestion focus on improving physiologic function via the promotion of acid production and enzymes rather than the suppression of secretions. Many common pharmaceutical prescriptions and over-the-counter drugs work to neutralize stomach acid or block its release from the gastric mucosa which may lower symptoms but also alter the gut microbiome and lead to decreased digestive function and nutrient absorption.

Healthy fats are vital for the proper function of the nervous and immune systems of blood type B, but stress, aging, and illness can block the adequate production of critical elements known to be required for proper lipid breakdown and assimilation.  That’s why TypeBase B, like the type AB and A formulas, uses a unique combination of ox bile and lipase to activate the production of critical lipolytic machinery.   

Breakdown of starches can be a problem with type B, so TypeZyme B supplies a significant dose of high-activity amylase, an enzyme that helps break down sugars and aids in gut repair. Like type O, the proper diet for type B requires significant protein, the breakdown of which can diminish with age and genetics. In both blood types, I’ve had very good clinical success using pancreatin, a mixture of several digestive enzymes produced by the secreting cells of the pancreas.  

Unique to TypeZyme B however, is the use of pancreatin from sheep sources, versus the type O formula, which uses pancreatin derived from cattle. Finally, as with all TypeZyme formulas, TypeZyme B rounds out with a synergistic dose of the plant enzyme bromelain, which helps condition the gut and acts like a gentle detergent throughout the digestive system.


TypeZyme B is useful for symptoms associated with maldigestion such as:

  • Acid Reflux
  • Indigestion
  • Bloating, Belching, Flatulence
  • Diarrhea or Constipation
  • Undigested food in stool
  • Acne
  • Hair Loss
  • Food Sensitivities
  • Nutrient Deficiencies

A low enzyme level can also create an environment optimal for specific bacterial infections. Restoring gastric acid, and effectively lowering the pH of the stomach, has been shown to prevent the overgrowth of organisms such as Helicobacter pylori, which is widely associated with gastritis, peptic ulcers, and gastric cancer. [7]


TYPICAL DOSAGE

2 capsules with lunch and dinner

PRODUCT HISTORY

This product was introduced by NAP in 2023.

REFERENCES

  1. Mills, J.C., & Stappenbeck, T.S. (2014). Gastrointestinal disease. In G.D. Hammer & S.J. McPhee (Eds.), Pathophysiology of disease: An introduction to clinical medicine (pp. 333-383). Columbus, OH: McGraw-Hill Education.
  2. Ianiro, G., Pecere, S., Giorgio, V., Gasbarrini, A., & Cammarota, G. (2016). Digestive Enzyme Supplementation in Gastrointestinal Diseases. Current drug metabolism, 17(2), 187–193. https://doi.org/10.2174/138920021702160114150137
  3. Camilleri M. Leaky gut: mechanisms, measurement and clinical implications in humans. Gut. 2019 Aug;68(8):1516-1526. doi: 10.1136/gutjnl-2019-318427. Epub 2019 May 10. PMID: 31076401; PMCID: PMC6790068.
  4. Delhaye, M., Meuris, S., Gohimont, A. C., Buedts, K., & Cremer, M. (1996). Comparative evaluation of a high lipase pancreatic enzyme preparation and a standard pancreatic supplement for treating exocrine pancreatic insufficiency in chronic pancreatitis. European journal of gastroenterology & hepatology, 8(7), 699–703.
  5. Park, S. Y., & Rew, J. S. (2015). Is Lipase Supplementation before a High Fat Meal Helpful to Patients with Functional Dyspepsia?. Gut and liver, 9(4), 433–434. https://doi.org/10.5009/gnl15206
  6. Wang, D. Q., & Carey, M. C. (2014). Therapeutic uses of animal biles in traditional Chinese medicine: an ethnopharmacological, biophysical chemical and medicinal review. World journal of gastroenterology, 20(29), 9952–9975. https://doi.org/10.3748/wjg.v20.i29.9952
  7. Park, S. Y., & Rew, J. S. (2015). Is Lipase Supplementation before a High Fat Meal Helpful to Patients with Functional Dyspepsia?. Gut and liver, 9(4), 433–434. https://doi.org/10.5009/gnl15206



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