NP048

Genoma Security


TAGS:    ANTIOXIDANTS/HERBAL FORMULAS    |   IMMUNITY    |   PULMONARY

To enhance healthy immunity

INTRODUCTION

A traditional herbal formula crafted by Dr. Peter D’Adamo from a balance of five well-researched herbal ingredients, Genoma Security is designed to gently enhance a healthy, balanced immune response. A blend of five well-researched herbs designed to enhance healthy immunity.


DESCRIPTION/ BACKGROUND

Andrographis paniculata Herb.  Since ancient times, A. paniculata is used in traditional Siddha and Ayurvedic systems of medicine as well as in tribal medicine in India and some other countries for multiple clinical applications. The therapeutic value of Kalmegh is due to its mechanism of action which is perhaps by enzyme induction. The plant extract exhibits anti-typhoid and anti-fungal activities. (1) Kalmegh is also reported to possess anti-hepatotoxic, anti-biotic, anti-malarial, anti-hepatitic, anti-thrombogenic, anti-inflammatory properties to mention a few, besides its general use as an immunostimulant agent.

Schisandra chinensis Fruit.  A renowned herb in Chinese medicine, Schisandra invigorates the RNA-DNA molecules to reconstruct cells and enhance the fitness of the adrenal glands. Adaptogenic herbs, like schisandra, have been used in Traditional Chinese Medicine to improve the ability of the body to respond to stress. (3) The major constituents in schisandra are lignans (schizandrin, deoxyschizandrin, gomisins, and pregomisin) found in the seeds of the fruit.

Atractylodis Macrocephalae Root.  Atractylodis is an herb used in traditional Chinese medicine, which helps lower blood glucose levels by increasing glucose assimilation. (5) Practitioners of Chinese medicine believe that Atractylodes affects the Spleen and Stomach meridians, or energy pathways in the body, serving as a “Spleen Qi tonic,” meaning that it rebuilds metabolic function by increasing nutrition, increasing energy, and regulating fluids.

Chinese Skullcap Root Extract (from Scutellaria baicalensis).  Chinese Skullcap flavonoid is a member of the mint family and has long been used in traditional Chinese herbal medicine, as a digestive aid, and to normalize an over-active digestive system.

Eleutherococcus senticosus Root. Eleutherococcus is also known as Siberian ginseng. The applicable parts of Siberian ginseng are the root and leaf. The root, which is most commonly used, contains active compounds referred to as eleutherosides A through M. (8) Eleutheroside B (syringin) and eleutheroside E (syringaresinol) are the most plentiful and are used as marker compounds for Siberian ginseng products. (9) The eleutherosides include a variety of diverse compounds including saponins (daucosterol, betasitosterol, hederasaponin B), coumarins (isofraxidin), lignans (sesamin, syringaresinol), phenylpropanoids (syringin, caffeic acid, sinapyl alcohol, coniferyl aldehyde, protocatechuic acid), betulinic acid, vitamin E, and provitamins like beta-carotene.



AGENT/ INGREDIENT ROLE
Schisandra fruit
Skullcap (Scutellaria baicalensis)
Eleutherococcus senticosus
Atractylodes rhizome
Andrographis paniculata

TABLE 1: Key agents in Genoma Security.

ACTIONS/ INDICATIONS

  • A recent study conducted at Bastyr University, confirms the anti-HIV activity of andrographolide. (2)
  • Modern Chinese research suggests these lignans have a protective effect on the liver and an immunomodulating effect. (4)
  • White atractylodes is also thought to have restorative, normalizing effects on the digestive system and Liver. (6)
  • Scutellaria has been shown to decrease inflammatory cytokine production from human mast cells (immune system hormones which ramp up inflammation). Scutellaria also has a cell-regulating effect; encouraging the body to more efficiently remove cells which have become dysfunctional, either though age or malformation. (7)
  • Siberian ginseng root, the lignin constituent sesamin, and the phenylpropanoid syringin seem to have immunostimulatory effects.

TYPICAL DOSAGE

1 capsule 2 times daily. Dr. D'Adamo has found the formula to be exceedingly effective in acute cases when sufficient blood levels are attained. This can accomplished by an initial loading dose of 3-4 capsules , followed by 2 capsules every two hours, gradually tapering off after a day or so.

PRODUCT HISTORY



REFERENCES

  1. Duke, J. A. et al. 2002. CRC Handbook of medicinal herbs. (CRC MedHerbs ed2)
  2. Howard, R. 1974–1989. Flora of the lesser Antilles. (F LAnt)
  3. Liu KT. Studies on fructus Schizandrae chinensis. Annex 12: Studies on fructus Schizandrae chinensis. Plenary lecture, World Health Organization (WHO) Seminar on the Use of Medicinal Plants in Health Care, Sept 1977
  4. Chang HM, But P (eds). Pharmacology and Applications of Chinese Materia Medica 1. Singapore: World Scientific, 1986.
  5. Fan, Warner J-W. A Manual of Chinese Herbal Medicine: Principles and Practice for Easy Reference. Boston: Shambhala, 1996.
  6. Holmes, Peter. Jade Remedies: A Chinese Herbal Reference for the West. Boulder, Colo.: Snow Lotus Press, 1996.
  7. Gao Z, Huang K, Xu H. Protective effects of flavonoids in the roots of Scutellaria baicalensis Georgi against hydrogen peroxide-induced oxidative stress in HS-SY5Y cells. Pharmacol Res. 2001; 43(2):173-178.
  8. Davydov M, Krikorian AD. Eleutherococcus senticosus (Rupr. & Maxim.) Maxim. (Araliaceae) as an adaptogen: a closer look. JEthnopharmacol 2000;72:345-93.
  9. Harkey MR, Henderson GL, Gershwin ME, et al. Variability in commercial ginseng products: an analysis of 25 preparations. Am J Clin Nutr 2001;73:1101-6.



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