BT005AB

TypeZyme AB


TAGS:    DIGESTION

ABO specific digestive enzyme complex

INTRODUCTION

The chemical process of digestion depends upon enzymes to break down complex food components (e.g., polysaccharides, fats, and proteins) into their absorbable forms (e.g., monosaccharides, fatty acids, and amino acids) for bodily use. These enzymes are secreted by cells or glands in the gastric mucosa as well as directly from exocrine glands including the salivary gland, pancreas, gallbladder, and liver. [1] Impediments to chemical digestion can lead to maldigestion, malabsorption, changes to the pH of the GI tract, and hence alterations to the microbiome.

Supplementing with digestive enzymes has been shown to improve digestion and restore balance when chemical digestion has been disrupted. This can lead to improvements in gastroesophageal reflux, dysbiosis, dyspepsia, and even inflammatory GI disorders. [2]

Typezyme formulas have been designed by Dr. Peter J. D’Adamo with blood type specificity in mind. His identification of blood-type-associated digestive patterns guided formulations that optimize nutrient breakdown and assimilation while reducing symptoms of maldigestion for each type.

Variations between the blood types regarding the production and array of digestive enzymes have been extensively reported in the medical literature. In fact, the level of certain digestive enzymes can vary by as much as a four-fold difference when one considers just   ABO blood type and secretor status. That’s why I thought it was important to develop a line of enzymes that took the strengths and weaknesses of each blood type into account. Now after over two years of development and testing, we’re ready to release these new TypeZyme formulas.

As with all DPN. Products, these formulas as assayed for potency, and screened for heavy metals and unwanted microbial activity. The individual ingredients have been sourced from around the world and selected by our technical team for maximum bioactivity. I believe these are the best digestive support formulas available.

 


DESCRIPTION/ BACKGROUND

  • Amylase- This is the main focus of this formula as carbohydrate digestion is where blood type O’s require the most support. Amylase is typically secreted from the salivary glands and pancreas and aids with metabolism of sugars and improves intestinal permeability. [3]
  • Lipase- Lipase is typically secreted by the pancreas to break down lipids. Supplementation with lipase has been shown to correct pancreatic insufficiencies and reduce bloating and discomfort following high fat meals. [4,5]
  • Bromelain- Bromelain is found in the stem and fruit of the pineapple (Ananas comosus) and is a known anti-inflammatory and digestive aid in instances of pancreatic insufficiency and other intestinal disorders. [6]
  • Ox Bile-  Ox bile has an ancient history of use in Traditional Chinese Medicine in the treatment of jaundice and intestinal parasites. It was also used to reduce hemorrhoids due to astringent properties. Modern use of ox bile has shown efficacy  in the treatment of steatorrhea as it is a fat emulsifier.[7]
  • Protease- This breaks proteins into amino acids. Protein maldigestion can lead to putrefaction in the gut and the production of toxic metabolites that are both inflammatory and disruptive to the microbiome. [8] Proteases are largely responsible for keeping the small intestine free from parasites (including bacteria, yeast, protozoa, and intestinal parasites).


AGENT/ INGREDIENT ROLE
Ox Bile

TABLE 1: Key agents in TypeZyme AB.

ACTIONS/ INDICATIONS

Although we're fond of describing the blood type AB food plan as the ‘best of both kingdoms,’  there are excellent reasons why it was called ‘The Enigma’ in Eat Right for Your Type.  Type AB works like type A here, type B there, and type AB everywhere else. Because of this, we designed  TypeZyme AB  to ‘cover all the bases,’  but in a way that also respected the unique characteristics of this rare blood type.

Like blood type A, type AB requires fat-breakdown support, so the formula features a significant dose of the fat-digesting enzyme lipase. Like type O, Type AB can have difficulties breaking down starches, so TypeZyme AB packs a significant dose of the starch-breakdown enzyme amylase, an enzyme that is normally found in saliva and the upper intestinal tract. As with type B, we’ve always enjoyed good clinical success with an old, time-tested digestive aid, ox bile, and have added a synergistic amount of this important fat emulsifier. Finally, the formula rounds out with a synergistic dose of the plant enzyme bromelain, which helps condition the gut and acts like a gentle detergent throughout the digestive system.

Typezyme AB is useful for symptoms associated with maldigestion such as:

  • Acid Reflux
  • Indigestion
  • Bloating, Belching, Flatulence
  • Diarrhea or Constipation
  • Undigested food in stool
  • Acne
  • Hair Loss
  • Food Sensitivities
  • Nutrient Deficiencies

A low gastric acidity level can also create an environment optimal for specific bacterial infections. Restoring gastric acid, and effectively lowering the pH of the stomach, has been shown to prevent the overgrowth of organisms such as Helicobacter pylori, which is widely associated with gastritis, peptic ulcers, and gastric cancer. [9]

 


TYPICAL DOSAGE

2 capsules with lunch and dinner

PRODUCT HISTORY

This product was introduced by NAP in 2023.

REFERENCES

  1. Mills, J.C., & Stappenbeck, T.S. (2014). Gastrointestinal disease. In G.D. Hammer & S.J. McPhee (Eds.), Pathophysiology of disease: An introduction to clinical medicine (pp. 333-383). Columbus, OH: McGraw-Hill Education.
  2. Ianiro, G., Pecere, S., Giorgio, V., Gasbarrini, A., & Cammarota, G. (2016). Digestive Enzyme Supplementation in Gastrointestinal Diseases. Current drug metabolism, 17(2), 187–193. https://doi.org/10.2174/138920021702160114150137
  3. Camilleri M. Leaky gut: mechanisms, measurement and clinical implications in humans. Gut. 2019 Aug;68(8):1516-1526. doi: 10.1136/gutjnl-2019-318427. Epub 2019 May 10. PMID: 31076401; PMCID: PMC6790068.
  4. Delhaye, M., Meuris, S., Gohimont, A. C., Buedts, K., & Cremer, M. (1996). Comparative evaluation of a high lipase pancreatic enzyme preparation and a standard pancreatic supplement for treating exocrine pancreatic insufficiency in chronic pancreatitis. European journal of gastroenterology & hepatology, 8(7), 699–703.
  5. Park, S. Y., & Rew, J. S. (2015). Is Lipase Supplementation before a High Fat Meal Helpful to Patients with Functional Dyspepsia?. Gut and liver, 9(4), 433–434. https://doi.org/10.5009/gnl15206
  6. Taussig SJ, Batkin S. Bromelain, the enzyme complex of pineapple (Ananas comosus) and its clinical application. An update. J Ethnopharmacol. 1998;22:191–203.
  7. Wang, D. Q., & Carey, M. C. (2014). Therapeutic uses of animal biles in traditional Chinese medicine: an ethnopharmacological, biophysical chemical and medicinal review. World journal of gastroenterology, 20(29), 9952–9975. https://doi.org/10.3748/wjg.v20.i29.9952
  8. Dallas, David & Sanctuary, Megan & Qu, Yunyao & Haghighat Khajavi, Shabnam & Zandt, Alexandria & Dyandra, Melissa & Frese, Steven & Barile, Daniela & German, Bruce. (2015). Personalizing Protein Nourishment. Critical reviews in food science and nutrition. 57. 10.1080/10408398.2015.1117412. 9
  9. Waldum, H. L., Kleveland, P. M., & Sørdal, Ø. F. (2016). Helicobacter pylori and gastric acid: an intimate and reciprocal relationship. Therapeutic Advances in Gastroenterology, 836–844. https://doi.org/10.1177/1756283X16663395



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