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NP082 Fish Oil BlendTAGS: ANTI-INFLAMMATORY | BRAIN | CARDIO | MUSCULOSKELETAL Supports healthy immune and cognitive function INTRODUCTION Our Fish Oil Formula is intended to offset the excess of omega-6 fatty acids found in the meats and many of the vegetable oils that are part of the Hunter and Explorer Diets, which can cause them to suffer a relative deficiency of omega-3’s. Particularly important to good health are the longer chain omega-3 fatty acids such as eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) found in fish, especially cold-water fish such as anchovies and sardines. Moving to a liquid-based formula allows us to bottle in very small numbers, insuring that the precious elements in the oils are not lost due to oxidation. It is cold pressed, and it is packaged in a light-resistant bottle to preserve the quality and freshness of the oils. Finally, Dr. Peter D’Adamo included hints of lemon oil and rosemary extract in the blend to create a great tasting oil that has tremendous health benefits. DESCRIPTION/ BACKGROUND The Marine Lipid Concentrate that makes up our Fish Oil Formula originates from wild fish caught in some of the purest water in the world, the untouched Deep Ocean waters of the South Pacific off the coast of Peru. This pharmaceutical-grade, marine lipid concentrate offers the assurance of meeting your requirements for these valuable, long-chain, omega-3 fatty acids without the fear of contamination from mercury, other heavy metals, lipid peroxides, PCB’s and other environmental toxins, or other harmful compounds. The two most important omega-3 fatty acids in human nutrition are eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). They are obtained in the human diet primarily in oily fish and their oils, especially from anchovies, cod liver, herring, mackerel, salmon, menhaden, striped bass, rainbow trout, halibut, tuna, and sardines. They are especially crucial for the production of healthy human breast milk and the development and health of the brain.(1) DHA in particular is essential for prenatal brain development and for healthy postnatal brain function. Sixty percent of the fatty acids that make up neuronal cell membranes of the retina consist of DHA, and it is found particularly concentrated in synaptic membranes.(2) In fact, the importance of these long-chain, omega-3 fatty acids to brain health is so clear that geographic areas where consumption of DHA is high are associated with decreased rates of depression.(3) In one double-blind, randomized, placebo controlled, parallel-group trial, researchers found a clear benefit of Fish Oil supplementation in reducing symptoms amongst depressed participants.(4) In another clinic trial for major depressive disorder, 1000mg of EPA daily had therapeutic effects controlling depressive symptoms equivalent to 20mg of Prozac.(5) In addition to their effects on depression, the long-chain omega-3 fatty acids found in Fish Oil are able to help patients suffering from mild Alzheimer’s disease. Diabetogenic and cholesterogenic diets replete with refined, high-glycemic load carbohydrates, long-chain saturated fatty acids, the omega-6 fatty acid arachidonic acid, and its prostaglandin metabolites have all been implicated in the pathogenesis of Alzheimer's disease. The DHA found in Fish Oil has been shown to oppose this process by exerting “a plethora of pleiotropic activities to protect against the pathogenesis of Alzheimer's disease.”(6) As current first-line medications for use in Alzheimer's disease are not particularly helpful and plagued by potentially dangerous side-effects, perhaps patients should consider the omega-3 fatty acids found in Fish Oil before starting cholinesterase inhibitors.(7,8) The omega-3 fatty acids have been shown to have an important capacity to modulate the inflammatory response, which is naturally increased in those of the Hunter and Explorer GenoTypes. One study that looked at dietary omega-3 fatty acid supplementation during pregnancy in mothers with a history of immune hyperreactivity found that Fish Oil alters the phenotype of the infant cord blood hematopoietic progenitors in a way that indicates a reduction of the child’s risk for the development of asthma and atopic disease.(9) Related studies have confirmed a reduction in subsequent infant allergies after maternal Fish Oil supplementation.(10) Another group of researchers found that DHA can obliterate the lethal nephrotoxicity induced by the chemotherapeutic agent Cisplatin and protect renal tissue from injury by reducing leukocytosis, systemic inflammation, and oxidative stress.(11) In addition to its benefits on cognitive function and inflammation, Fish Oil has benefits on maintaining healthy levels of cholesterol and promoting heart health. A 6-month, randomized, double-blind, placebo-controlled clinical trial of 124 elderly found that daily Fish Oil could significantly decrease serum triglyceride levels, one of the main cardiovascular disease risk indicators for the Hunter and Explorer GenoTypes.(12) Daily Fish Oil supplementation was shown in another study to lower blood pressure and increase levels of the beneficial HDL “cholesterol” after only 16 weeks.(13) In a large-scale clinical trial, the omega-3 fats in Fish Oil were found to reduce mortality and admission to the hospital for cardiovascular reasons in patients with chronic heart failure. The researchers attributed the benefits of Fish Oil to its antiarrhythmic action and its ability to positivity influence “the mechanisms related to heart failure progression.”(14) Cardiac specialists have estimated that raising omega-3 fatty acid levels via regular Fish Oil supplementation would have about eight times the impact of distributing automated external defibrillators (AED’s) and two times the impact of implanting cardioverter-defibrillators (ICD’s) in appropriate candidates. In addition, they confirmed that raising omega-3 fatty acid levels would also reduce rates of sudden death amongst those who do not qualify for ICD’s.(15)
TABLE 1: Key agents in Fish Oil Blend. Our new Fish Oil Blend is a powerhouse combination of cod liver oil and fish oils, derived from wild-caught cod, sardines and anchovies from the pristine waters off the coast of Peru. It provides the highest quality and the perfect combination of the Omega 3 fatty acids EPA and DHA, and it delivers close to three times the level of DHA and EPA that we had in our capsules. Fish oil is well known for its overall health benefits, particularly the maintenance and support of: Heart and cardiovascular health Enhancing normal brain function Healthy joint function Visual health Healthy hair and skin Moving to a liquid-based formula allows us to bottle in very small numbers, insuring that the precious elements in the oils are not lost due to oxidation. It is cold pressed, and it is packaged in a light-resistant bottle to preserve the quality and freshness of the oils. Finally, Dr. Peter D’Adamo included hints of lemon oil and rosemary extract in the blend to create a great tasting oil that has tremendous health benefits. Our Fish Oil Blend Liquid: Pure, pharmaceutical grade marine lipids. A perfect combination of the omega 3 fatty acids EPA and DHA. Supports heart health, normal brain function, and positive mood. Easy to take liquid formula - blended with lemon oil and rosemary extract for a pleasant taste. Healthy without sacrificing taste.
TYPICAL DOSAGE 1 to 2 teaspoons daily. It can also be mixed with a favorite juice, salad dressing, or smoothie. Higher doses can be used for therapeutic purposes. PRODUCT HISTORY Introduced in 2014 for use in the Center of Excellence in Generative Medicine REFERENCES
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